The Protein Cost of Metabolic Fluxes: Prediction from Enzymatic Rate Laws and Cost Minimization
Table 1
The fitness unit Darwin (D) is a proxy for the different fitness units used in cell models. Reaction must be orientated in such a way that all fluxes are positive. To define metabolite log-concentrations, we use the standard concentration cσ = 1 mM. For a more comprehensive list of mathematical symbols used in ECM, see Table C in S1 Text.