Genetic Redundancies Enhance Information Transfer in Noisy Regulatory Circuits
Fig 3
The distribution of the signal modulates the increase of information transfer due to genetic redundancy.
(A) Effect of the form of the distribution on MI: (1) uniform (covering two orders of magnitude), (2) lognormal (with standard deviation equal to 2/3), and (3) beta in log scale (with the two shape parameters equal to 1/3). In all cases, the mean of the distribution is equal to the threshold value. (B) Effect of the mean of the distribution (here uniform) on MI: (1) equal to the threshold value, (2) and (3) deviated from the threshold value. We considered as threshold device a bistable unit implemented with a positive feedback in all plots (Materials and Methods).