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Interrogating Emergent Transport Properties for Molecular Motor Ensembles: A Semi-analytical Approach

Fig 10

Average Run-length under different load forces on a cargo with ensembles of three motors, wild type and mutant (WWW, WWM, WMM and MMM).

(A) Average Run-length of ensembles subjected to load forces around 2.2 pN. Ensembles with a higher proportion of mutant motors demonstrate lower average run-length than the rest of the ensembles. (B) Average Run-length of ensembles subjected to load forces around and Fs = 6 pN. Near , ensembles with more mutant motors travel farther, whereas near Fs = 6 pN, ensembles with more wild-type motors travel farther. (C) Average Run-length of ensembles subjected to load forces around and 2Fs = 12 pN. Again, near , ensembles with more mutant motors travel farther, whereas near 2Fs = 12 pN, ensembles with more wild-type motors travel farther.

Fig 10

doi: https://doi.org/10.1371/journal.pcbi.1005152.g010