Mechano-chemical Interactions in Cardiac Sarcomere Contraction: A Computational Modeling Study
Fig 5
MechChem generated [Ca2+]-tension relationship in skinned muscle.
The MechChem model generated [Ca2+]-tension relationship with KTnCa0 changing with SL, while setting Cf = 1.93∙106 m-1S and Cs = 6.5 S-1. The unit S refers to the unit of tension as shown by Dobesh et al. [18]. The dots on the curve are plotted from the data presented in Table 2 and Fig 2A of Dobesh et al. 2002 [18].