Mechano-chemical Interactions in Cardiac Sarcomere Contraction: A Computational Modeling Study
Fig 4
Static [Ca2+]-tension relationship in skinned muscle.
(A). The MechChem model generated [Ca2+]-tension relationship with all parameters fitted per curve. The dots on the curve are plotted from the data presented in Table 2 and Fig 2A of Dobesh et al. 2002 [18]. (B) Hill model generated [Ca2+]-tension curves. The experimental data points from Fig 4A were superimposed on the model generated curves. The error between the experimental data and both the (C) MechChem model generated [Ca2+]-tension curves and (D) the Hill model generated [Ca2+]-tension curves is shown.