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Data-Driven Metabolic Pathway Compositions Enhance Cancer Survival Prediction

Fig 2

Comparing the performance of MCF to MGE-SVM across integrated cancer-type datasets.

(A) A bar plot describing the predicted AUC obtained over the combined datasets of the same cancer type using a five-fold cross validation procedure for MGE-SVM (red bars) and MCF (blue bars) classifiers. AUC denotes the area under the curve. Error bars represent one standard deviation, and p-values are for a one-sided, paired-sample t-test for the AUC of each of the five folds. (B), (C) present the receiver operating characteristic (ROC) curves obtained in the classification of the lung and breast cancer combined datasets, respectively.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1005125.g002