SUMOFLUX: A Generalized Method for Targeted 13C Metabolic Flux Ratio Analysis
Fig 5
Optimizing experimental design to improve the estimation of three flux ratios in Bacillus subtilis central carbon metabolism.
Mean absolute errors on the test dataset of three flux ratio predictors applied to in silico data simulated with different experimental setups. GC-MS—gas chromatography mass spectrometry, LC-MS—liquid chromatography mass spectrometry; LC-MS/MS—liquid chromatography-tandem mass spectrometry; LC-MRM—liquid chromatography with multiple reaction monitoring information; MAE—mean absolute error; PPP—pentose phosphate pathway.