Adaptive Remodeling of Achilles Tendon: A Multi-scale Computational Model
Fig 2
Tendon adaptation modeling cycle.
a) discretized tendon model, b) force-extension response of the tendon model, c) three-component Hill musculotendon model, d) metabolic rate calculation model, e) model to scale contractile force from muscle, f) collagen fiber mechanical damage model and, g) collagen fiber proteolytic damage and repair model, h) updated tendon fiber length distribution results in a new tendon configuration and completion of a remodeling cycle of tendon adaptation model. Where PDF is probability density function, LS represents tendon slack length that is equal to the slack length of the shortest fiber, SD represents fiber length standard deviation, a measure of fiber dispersion, and Li represents fiber slack length.