A Computational Model of Hepatic Energy Metabolism: Understanding Zonated Damage and Steatosis in NAFLD
Fig 3
(a) The effects of simulating IR on total hepatic metabolism (averaged across the sinusoid). (b) The heterogeneity in the effects of simulating IR across the sinusoid. (c) The effects of simulating increasing severities of IR on plasma triglyceride, glucose and FFA concentrations compared with experimental data from Sindelka et al [65] and Burnt et al. [66].