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A Computational Model of Hepatic Energy Metabolism: Understanding Zonated Damage and Steatosis in NAFLD

Fig 2

Variables and conversions included in each hepatic compartment.

In addition to the hormonal regulation, almost all of the glucose and lipid metabolism conversions show some form of allosteric regulation. Lipolysis is also included but it occurs at very slow rate in hepatocytes.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1005105.g002