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Noncommutative Biology: Sequential Regulation of Complex Networks

Fig 6

Scaling in the sequestration model is super-exponential.

(A) A plot of all the allowed configurations of a set of targets of n = 4 regulator pairs in the sequestration model. Yellow represents targets that are ON, and blue those that are OFF. (B) A list of the sequences generating the corresponding states in A. K actions are shown in the red spectrum, and P in the blue. (C) A logarithmic plot of the scaling in the sequestration model. The total space is the 22n − 1 − 1, the reachable space is calculated from Eq (7), and the combinatorial model is 22n.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1005089.g006