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A Parsimonious Model of the Rabbit Action Potential Elucidates the Minimal Physiological Requirements for Alternans and Spiral Wave Breakup

Fig 1

Dynamic I-V curves from isolated cells.

A) Transmembrane potential (Vm) recorded during the action potential upstroke from six isolated rabbit cells from [43]. B) Current-voltage (I-V) relationship plotted as INa (models: lines) or (experiments: ●) versus Vm. C) Predicted Vm signals from models (lines) and average from experiments (●) during the upstroke.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1005087.g001