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Inference of Ancestral Recombination Graphs through Topological Data Analysis

Fig 11

Parameter estimation in models of evolution.

(A) Dependence of on the recombination rate parameter for a set of 1,000 simulations of a basic coalescent model. Each simulation consists of 200 sequences, 30 kilobase long. The expected of the barcode ensemble grows monotonically with the recombination rate, providing a good measure of the later. The smoothed average is shown in red. (B) Dependence of the average death time, 〈ϵd〉, on the migration rate of two divergent populations with fixed recombination and variable migration rates, based on 900 simulations. Each simulation consists of 150 sampled sequences, 10 kilobase long. The same structure as in Fig 8 was considered for the two populations. The expected value of 〈ϵd〉 decreases monotonically with the migration rate, being informative of the later.

Fig 11

doi: https://doi.org/10.1371/journal.pcbi.1005071.g011