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Symbiotic Cell Differentiation and Cooperative Growth in Multicellular Aggregates

Fig 5

Growth enhancement with network 1 (D = 1).

(A) Dependence of Rμ on parameters C and V. Cells can differentiate given the parameters to the left of the green line. (B) Dependence of Rμ on V (C = 0.1). Rμ is the ratio of the growth rate of differentiated cells to that of isolated cells. (C) Dependence of Rp on V (C = 0.1). Rp is the degree of increase in the production of X3-X4 conferred by differentiation.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1005042.g005