Evolutionary and Topological Properties of Genes and Community Structures in Human Gene Regulatory Networks
Fig 4
Interset efficiency and age for AML 2.3.
Interset efficiency from DAVID group in column j to DAVID group in row i. The list of DAVID groups was sorted by average age from oldest (transcriptional elongation) to youngest (hemoglobin complex). Old DAVID groups exchange information efficiently, as indicated by the high interset efficiency values in the lower-left corner. Younger DAVID groups, particularly the blood cell-specific DAVID groups of lymphocyte activation and hemoglobin complex, are remote from most other DAVID groups. Note that the above matrix is asymmetric because the network is directed, and that the colors are log-scaled.