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Inverse Stochastic Resonance in Cerebellar Purkinje Cells

Fig 7

ISR leads to local optimum of mutual information between the input and output spike train.

A, B, C. Voltage traces (top) of the aEIF model in response to series of excitatory synaptic inputs (middle, amplitude Am = 100 pA), in addition to background stimulation by noise with amplitude σ = 10 pA, 30 pA and 60 pA (bottom). D. Mutual Information (MI) of the input and output spike train of the aEIF model. E. MI as a function of the decay time constant (duration of a spiking state). Remark: two data points corresponding to σ = 0 pA, 100 pA are not shown (as in Fig 6E). For σ = 0 pA the duration of the stimulus-induced spiking state is infinite, while for σ = 100 pA the duration of this state could not be distinguished from the firing baseline.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1005000.g007