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Inverse Stochastic Resonance in Cerebellar Purkinje Cells

Fig 6

ISR transforms brief inputs into long-term firing states depending on background noise.

A, B, C. Characteristic voltage traces of the aEIF model in response to a single synaptic excitatory input in the presence of different levels of background noise with amplitude σ = 10 pA, 30 pA and 60 pA. Bottom, corresponding probability of spiking for a range of input amplitudes (color code). D. Maximal probability of state transition vs. synaptic input amplitude for 3 background noise amplitudes, E. Decay time constant for the duration of the spiking state induced by a synaptic input of 100 pA. Remark: two data points corresponding to σ = 0 pA, 100 pA are not shown because for σ = 0 pA the duration of stimulus-induced spiking state is infinite, while for σ = 100 pA the duration of this state could not be distinguished from the firing baseline.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1005000.g006