Cellular Interrogation: Exploiting Cell-to-Cell Variability to Discriminate Regulatory Mechanisms in Oscillatory Signalling
Fig 7
Amplitude analysis rules out class 2 models.
(A) Histograms of the amplitude decay rates for all the models (for better comparison, a superimposed black contour of the experimental histogram in Fig 6C has been added to each panel). The histograms show the frequency with which a particular decay rate is found, under uniform (left) and lognormal (right) sampling of initial conditions and parameter values. (B) Distance measure Δ (left) and KS statistic (right) between the histograms of each of the 8 models and EXP for uniform (top) and lognormal (bottom) sampling.