Cellular Interrogation: Exploiting Cell-to-Cell Variability to Discriminate Regulatory Mechanisms in Oscillatory Signalling
Fig 3
Models of oscillatory Ca2+ spiking.
Eight schematic molecular networks are shown; citations to the original papers are given in S1 Text along with detailed mathematical descriptions. Yellow discs or disc-segments show the dynamical variables in each model. Thick black arrows show fluxes of Ca2+ between compartments or fluxes between phospho-inositol moieties; arrows with no source or no target show Ca2+ fluxes from or to, respectively, the extra-cellular compartment. Dashed lines show positive (blue, arrow) and negative (magenta bar) influences; additional positive or negative influences may arise through the details of the mechanism behind each individual flux. Abbreviations are as in Fig 1A.