PhyloBot: A Web Portal for Automated Phylogenetics, Ancestral Sequence Reconstruction, and Exploration of Mutational Trajectories
Fig 1
Summary of PhyloBot automated pipeline.
A user begins by uploading a collection of orthologous protein sequences in a FASTA-formatted text file. PhyloBot reads the sequence collection and launches its automated analysis pipeline, which includes sequence alignment, phylogenetic model-fitting, tests of branch support, ancestral sequence reconstruction, and prediction of functional genetics. Upon completion, the results can be viewed in a web browser.