PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions
Fig 4
Performance of nucleotide-based and protein-based prediction tools and their consensuses, evaluated using the dataset of variants associated with Mendelian diseases.
(A) Observed normalized accuracy and (B) area under the receiver operating characteristic curve (AUC) values are shown as blue and red bars for nucleotide- and protein-based tools and their consensuses, respectively. The horizontal dashed lines represent average performance values for each tool type.