Structural Determinants of Misfolding in Multidomain Proteins
Table 1
Summary of misfolding statistics and central domain properties.
K labels the type of fold/misfold (see text; K = 0 is native); RCO is relative contact order [49]. ΔGf and ΔGs are the folding barrier and stabilities of a single folded/misfolded domain. Population is frequency of each state at the end of the 1024 trajectories. Maximum standard error on populations is 1.6% for a sample size of 1024. Numbers in brackets are rank correlations with folded/misfolded populations.