A Detailed Data-Driven Network Model of Prefrontal Cortex Reproduces Key Features of In Vivo Activity
Fig 3
Spiking statistics of simulated PFC model networks.
(A) Comparison of relative frequency histograms for three different spike time statistics between recordings from an in vivo experiment (gray, see text for details) and from the simulation with input currents Iex = 250 pA, Iinh = 200 pA (black). The shaded region represents the mean ± the SEM at each point of the experimental distribution. (B) Raster plot of the spike times over the last six seconds of the simulation. The two layers (L2/3 and L5) are separated by a black line, pyramidal cells (PC) are in black, interneurons (IN) in gray. (C) Auto-correlation function of the inter-spike intervals of the experimental recordings (gray) and the network simulations (black).