A Detailed Data-Driven Network Model of Prefrontal Cortex Reproduces Key Features of In Vivo Activity
Fig 2
Anatomical and synaptic properties.
(A) Laminar structure of a single network column. Arrow widths represent relative strength of connections (black: excitatory, gray: inhibitory), i.e. the product of connection probability and synaptic peak conductance. (B) Left panel: Distribution of three different short-term plasticity types over different combinations of pre- and postsynaptic neuron types. Arrows from or to one of the shaded blocks (rather than from or to a single neuron type) denote connection types that are identical for all excitatory (PC) or inhibitory (IN) neurons. Where all three types are drawn, they are randomly distributed over all synapses between these two neuron types according to the probabilities given in the figure. Right panel: Illustration of the postsynaptic potential in response to a series of presynaptic spikes for three types of short-term synaptic plasticity for excitatory (E1 to E3) and inhibitory synapses (I1 to I3).