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Biophysical Network Modelling of the dLGN Circuit: Different Effects of Triadic and Axonal Inhibition on Visual Responses of Relay Cells

Fig 1

Schematic of the dLGN circuit model.

(Top) Five relay cells (RCs) receive input from one retinal ganglion (GC) cell each. All inputs to RCs arrive in triadic synapses, involving the one and same IN. In addition, the IN receives proximal input from all five GCs. The boxes highlight the synaptic connections in the networks and the associated connection weights w. Note that in the present model application, only responses for the central RC cell is considered so that the only effect of the four peripheral GCs comes from the proximal inputs to the IN. (Bottom) The GCs are organized with four peripheral GCs all located at distance ra from the center GC.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1004929.g001