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Computing Average Passive Forces in Sarcomeres in Length-Ramp Simulations

Fig 2

Solution of Eq (3) for stretches from 1μm to 2μm half sarcomere lengths.

Force [pN] of single titin strands at a given half sarcomere length is a discrete random variable with 51 states. The top curve represents the state in which all Ig domains are folded, the next curve the state in which exactly one Ig domain is unfolded, etc.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1004904.g002