A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells
Fig 6
Integration of CNV, polarized genes, mRNA expression and tumour features.
The figure summaries the relationship between gene CNV (blue), mRNA re-expression following hypo-methylating agents (yellow), polarized gene expression (red and green nodes are positively and negatively polarized genes, respectively) and tumour features (cyan). These relationships are the result of the statistical modeling described in the last section of the Results. Genes within the blue open rectangle (a) are under the influence of CNV and are linked to tumour features. Table 1 lists the genes within panel a and their functional classification according to Gene Ontology.