Quorum-Sensing Synchronization of Synthetic Toggle Switches: A Design Based on Monotone Dynamical Systems Theory
Fig 10
Self-correction of spontaneous errors by S toggles.
Panel (A) shows the S toggle which cannot self-correct a (9:1)-spontaneous synchronization error for a small value of the diffusion parameter d = 0.01 (a weak coupling between all cells). Panels (B) and (C) show the S toggle which can self-correct a (9:1)-spontaneous synchronization error for a medium (d = 10) and large (d = 100) values of parameter d (a medium and strong coupling between all cells, respectively). For the values of parameter d used in Panels (B) and (C), the mixed states become unstable, see Fig 9.