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Quorum-Sensing Synchronization of Synthetic Toggle Switches: A Design Based on Monotone Dynamical Systems Theory

Fig 8

An interpretation of symmetry breaking in a (1:1)-mixed population of S toggles.

A new (1:1)-asymmetric mixed state arises, in which there are two subpopulations, one in which green gene-expression dominates (but with different expression levels of LacI in each of them), and another one which red gene-expression dominates (also with different TetR levels).

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1004881.g008