MEDYAN: Mechanochemical Simulations of Contraction and Polarity Alignment in Actomyosin Networks
Fig 4
A flow diagram of a MEDYAN simulation.
(1) After the chemical stochastic simulation evolves the network in time and (2) local deformations are formed, (3) a mechanical equilibration is performed and (4) reaction rates are updated according to chosen functional forms f(Fcurrent) where Fcurrent is the force on that reacting molecule after equilibration.