CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing
Fig 5
CNVkit copy ratios agree with experimental results array CGH and FISH on cell line DNA.
A: Whole-genome profiles of log2 copy ratio by CNVkit (top) and array CGH (bottom) are shown. B: Genes additionally assayed by FISH are labeled with the detected absolute copy number. At CDKN2A, log2 ratios below the marked level of -3.58 indicate the site is entirely deleted in the majority of cells.