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A Well-Defined Readily Releasable Pool with Fixed Capacity for Storing Vesicles at Calyx of Held

Fig 1

Stimulus artifact elimination.

A. Sequence of examples of isolated EPSCs without KYN, in 1mM KYN, in 25μM CNQX, and the difference trace obtained by digitally subtracting the recording in CNQX from the recording in 1mM KYN. B. EPSCs during 300Hz stimulation; artifacts were removed by blanking a window of 1ms for traces in 1mM KYN and 0.5ms for the difference traces. C. Integral of sequential 3.33ms segments vs time of stimulation for traces in 1mM KYN and of the difference after subtracting matching traces in CNQX (n = 5 preparations). D. Ratio of corresponding integrals for traces in 1mM KYN and the difference traces vs time of stimulation.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1004855.g001