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Modeling the Excess Cell Surface Stored in a Complex Morphology of Bleb-Like Protrusions

Fig 5

Schematic for the phase field formulation of a cell in an aqueous medium.

ϕ1, ϕ2, ϕ3, represent volume fractions of the external aqueous medium, the nematic cortex as schematically depicted by the cross-hatched region and the cytosol, respectively, with ϕ1+ϕ2+ϕ3 = 1. The entire computational domain is denoted as Ω. The cell surface is defined by the level sets ϕ1 = ϕ2 = 0.5, while the cortex-cytosol interface is defined by ϕ2 = ϕ3 = 0.5. Note that we penalize coexistence of three phases.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1004841.g005