Modeling the Excess Cell Surface Stored in a Complex Morphology of Bleb-Like Protrusions
Fig 4
BLiPs morphology generated by seed-and-growth models.
A. A realization of the Voronoi diagram. The seeds and boundaries of Voronoi cells are shown in blue; the Voronoi polygons are shown in red. B. A realization of the “seed and growth” model. C. Magnified view of rectangle in (B). D. Distribution of BLiP sizes: Voronoi model (green bars) and “seed and growth” model (red bars) normalized using the assumption that average rounded cell radius is 8 um; the blue line shows the experimentally obtained distribution. E. For the “seed and growth” model, plots of % surface area stored in BLiPs and % of total volume stored in BLiPs as a function of the number of BLiPs. F. A cross-section of “seed and growth” model. G. Transmission electron micrograph of a section of a rounded cell (Bar = 2 μm) for comparison to F.