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APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone

Fig 9

Scheme illustrating the regulatory role of APP in a context-sensitive manner at the hippocampal PAZ. R, regulator; M, mediator, C, central player.

Color code: magenta, upregulation (in APP-mutants); green, downregulation (in APP-mutants); yellow, unaltered.

doi: https://doi.org/10.1371/journal.pcbi.1004832.g009