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APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone

Fig 5

Relative abundance of proteins mapped to the subcommunity structure of the network.

The size of the rings corresponds to the respective number of proteins. Communities were subdivided into functional clusters according to Fig 5. A Impact of APP deletion. B Impact of the NexCre-cDKO. Change in abundance of more than ±10% is reflected by increasing sizes of nodes. The color code corresponds to the degree of up- (magenta) and downregulation (green). Nodes in yellow represent proteins with changes in abundance of less than ±10%.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1004832.g005