QuIN: A Web Server for Querying and Visualizing Chromatin Interaction Networks
Fig 4
Comparison of ChIA-PET gene targets with nearest gene targets.
(A) A cartoon describing different approaches to associate NCVs with gene targets (Nearest TSS, Direct Targets, & Indirect Targets). (B) Enrichment p-values (based on Fisher’s exact test) of cancer related genes (known oncogenes (green), tumor suppressor genes (blue), poor prognosis genes (red), and the combined gene list (purple)) among NCV gene targets obtained via nearest TSS, direct target, indirect target associations. (C) Boxplot showing the differential expression (between cancer and normal tissues) for NCV target genes obtained via nearest TSS, direct target, indirect target associations.