Genetic Correlations Greatly Increase Mutational Robustness and Can Both Reduce and Enhance Evolvability
Fig 7
Non-neutral local mutational neighbourhood correlations result in mutational neighbourhoods of neutral neighbours being more similar than randomly selected neutral pairs.
We present results for the three GP maps: A) RNA20, B) S3,8 and C) HP5x5. Using the ratio of Bhattacharyya coefficients defined in Eq (10), we show that neutral neighbours (g and h) have a closer phenotype probability distribution than a randomly chosen neutral pair (g and g2). This is seen through the ratio being skewed with a mean (coloured vertical dashed lines) larger than unity (black vertical dashed lines). The standard error on this mean is negligible compared to the distance of the mean from one.