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Estimation of Directed Effective Connectivity from fMRI Functional Connectivity Hints at Asymmetries of Cortical Connectome
Fig 9
Robustness of estimated EC with respect to the EC density and individual FC.
A Fit performance as a function of the density of EC. The blue curve indicates the Q error for optimizations with several masks for C (x-axis); the error bar correspond to the 4 τest > 0. The red curve indicates the similarity between the estimated C and the empirical 
. B Similarity of estimated C measured by the Pearson correlation for the different masks in A and τest = 4 s. C Input-output asymmetry of the estimated C obtained for various optimization masks (error bars) and τest (x-axis). The red curve corresponds to LO and the purple curve to the heuristic method. The blue curve indicates the asymmetry of the empirical FCτ. D Q Error for LO based on individual FCs with τest = 2 and 4 s with 32% density. The horizontal dashed line corresponds to the Q error in Fig 7. E Similarity between the individual ECs and the EC obtained from the mean FC in Fig 7F. Similarity is measured by the Pearson correlation between the non-zero EC weights for the 32% density mask. F EC asymmetry of the individual ECs. The horizontal dashed line indicated the asymmetry of the EC in Fig 7F. G Agreement between the mean EC over individual FCs and the EC estimated from the mean FC.
doi: https://doi.org/10.1371/journal.pcbi.1004762.g009