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Stability and Competition in Multi-spike Models of Spike-Timing Dependent Plasticity

Fig 7

The NMDAR-based model.

A. Schematic illustration of spike interactions in the NMDAR-based model. The presynaptic spike up-regulates frest, activates Mdn and depresses the synapse. The postsynaptic spike down-regulates frest, activates Mup and potentiates the synapse. B. Plasticity in the NMDAR-based model due to triplets of spikes with parameters as in Table 2. The effect is asymmetric, with pre-post-pre triplets inducing potentiation (top left) and post-pre-post depression (bottom right).

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1004750.g007