PSAMM: A Portable System for the Analysis of Metabolic Models
Fig 4
Distribution of blocked reactions in metabolic pathways.
The GEMs were represented in each metabolic pathway as a solid circle. The color of the circles corresponds to the year in which a GEM was published (color legend was shown on the right, and the year of publication ranges from 2003 to 2014). The area of the circle is proportional to the total number of reactions in the pathway, and its vertical position indicates the fraction of reactions that are blocked. The median fractions were indicated by a red mark for each pathway, and models discussed in the main text were highlighted.