Ensembler: Enabling High-Throughput Molecular Simulations at the Superfamily Scale
Fig 4
Template-target sequence identity distribution for human tyrosine kinase catalytic domains.
Sequence identities are calculated from all pairwise target-template alignments, where targets are human kinase catalytic domain sequences and templates are all kinase catalytic domains from any organism with structures in the PDB, as described in the text. A kernel density estimate of the target-template sequence identity probability density function is shown as a solid line with shaded region, while the corresponding cumulative distribution function is shown as a dashed line.