Evolutionary Genomics Suggests That CheV Is an Additional Adaptor for Accommodating Specific Chemoreceptors within the Chemotaxis Signaling Complex
Fig 6
Analysis of the sequence conservation between CheW and CheVW.
A) Sequence logo of CheVW (top logo) and CheW (bottom logo). Positions conserved in both groups (20, 22, 24, 25, 27, 30, 35, 38, 39, 49, 57, 62, 67, 70, 71, 102, 105, 111, 132, 148, 151) (blue circles) and position conserved within each groups (28, 32, 33, 34, 36, 37, 41, 42, 50, 51, 54, 58, 61, 66, 68, 86, 89, 91, 92,98, 99, 100, 101, 104, 108, 110, 116, 133, 135, 142, 144, 145, 147, 149, 150) (red stars) are highlighted. Numbers for E. coli CheW. Proposed CheW regions for binding CheA [24, 58] and chemoreceptors [24, 50] are underlined in dashed and solid lines, correspondingly. B) Mapping of marked positions onto E. coli CheW NMR model [57] in ribbons (top) and accessible surface area (bottom).