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Evolutionary and Functional Relationships in the Truncated Hemoglobin Family

Fig 6

Collapsed phylogenetic tree of trHbs annotated with their key physicochemical characteristics.

The circular phylogram shows the topology derived from Fig 2A, with color-matched boxes indicating hierarchical clustering. values are mapped on the inner concentric circle using a violet color gradient (greater stabilization, darker violet). Tunnel apertures are mapped as red, cyan and light green dots for Long Tunnel, Short Tunnel G8 and E7 Gate, respectively, on the other concentric circles. Dot size indicates tunnel openness.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1004701.g006