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Capabilities and Limitations of Tissue Size Control through Passive Mechanical Forces

Fig 2

Vertex model of posterior compartment dynamics during the last division cycle in the Drosophila embryonic epidermis.

(A) Snapshot of the initial tissue configuration for each simulation, with mechanical parameters in Eq (3) annotated. (B) Schematic diagram of a junctional rearrangement (T1 swap), a cell removal (T2 transition), and cell division in the vertex model. Numbers indicate cell indices. (C) Snapshot of a wt simulation at the final time point, once all cell divisions have occurred, with annotation for the front and back halves of the P compartment. Parameter values are listed in Table 1.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1004679.g002