A Computational Model for the AMPA Receptor Phosphorylation Master Switch Regulating Cerebellar Long-Term Depression
Fig 5
Effect of PTPMEG on LTD expression.
(Total AMPAR plasma membrane population includes both phosphorylated, at either GluA2-Y876 or GluA2-S880, and unphosphorylated AMPARs.) (A) LTD expression in a PTPMEG-null system. (B) LTD expression in a PTPMEG-active system. (C) Changes in AMPAR phosphorylation state during LTD induction.