Red Queen Processes Drive Positive Selection on Major Histocompatibility Complex (MHC) Genes
Fig 5
Persistence of MHC allelic lineages.
(A) Fraction of allele pairs with no common ancestor within 40 000 generations (red, green, and blue symbols) and 250 000 generations (gray symbols, run only for the highest mutation rate of 5e-3) and (B) coalescence times for studied scenarios given in the legend (HA–heterozygote advantage, RQ–Red Queen, HA+RQ–both).