Unbiased Rare Event Sampling in Spatial Stochastic Systems Biology Models Using a Weighted Ensemble of Trajectories
Fig 5
Realistic cell geometry generated from microscopy images by CellOrganizer. The geometry explicitly models the compartmentalization of the cell, by forcing molecules to diffuse through membranes to transition from, for example, the cytoplasm (grey) to the nucleus (blue). Also modeled are endosomes (green), and the extracellular environment (transparent).