Unbiased Rare Event Sampling in Spatial Stochastic Systems Biology Models Using a Weighted Ensemble of Trajectories

doi:10.1371/journal.pcbi.1004611

Unbiased Rare Event Sampling in Spatial Stochastic Systems Biology Models Using a Weighted Ensemble of Trajectories

Fig 4

Toy model geometry.

This toy system has receptors at the top and bottom of a cubical “cell”. The receptors at the top are initially bound by ligands, that are free to unbind and diffuse around the cell, and bind to receptors at the bottom.

doi: https://doi.org/10.1371/journal.pcbi.1004611.g004