Fluctuation-Driven Neural Dynamics Reproduce Drosophila Locomotor Patterns
Fig 5
Dynamical mechanisms for reproducing Drosophila locomotor patterns.
(A) Network activity, locomotion, and population-averaged locomotor patterns in the absence (top) or presence (bottom) of fluctuations. ‘Individual network activity’ plots show neural activity trajectories during odor stimulation starting from ten color-coded initial conditions. Solid circles indicate the starting points of each trajectory. ‘Individual locomotion’ plots show locomotor patterns for two representative virtual flies in the absence (top) or presence (bottom) of fluctuations. ‘Population average’ shows the locomotor frequency averaged across 200 virtual flies in the absence (top) or presence (bottom) of fluctuations. (B) Odor-evoked locomotor pattern of the best fluctuation-driven model (Class 1) tuned to match the locomotor pattern of Drosophila strain A. Color-coded are periods of pre-odor basal locomotion (green), odor impulse (blue), locomotor decay (cyan) and post-odor reduced basal locomotion (magenta). (C) Trajectory density plots and (D) phase portraits for this model during each time period indicated in panel B. In trajectory density plots, arrowheads highlight increased neural activity not observed during pre-odor basal locomotion. These are further labeled as being above (white) or below (red) the threshold for walking. In all phase portraits, grey lines with arrows are trajectories that indicate the direction of flow in phase space.